Swiftly receive sections as slender or thick as your application necessitates, without stressing about getting rid of or distorting precious tissue samples.
Megatome is really a vibrating microtome meant to area a broad array of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome permits superior-throughput tissue sectioning with uniform floor profile, in addition to minimal tissue problems and data loss.
Request a quotation or demo Uniformly area huge tissues & sample arrays Megatome is the sole microtome that could area samples as significant as intact nonhuman primate and human organs, which makes it invaluable for fields which include neuropathology.
Functioning the CLI directly from a Gradle task is just not presently supported. A distribution need to be created through gradlew :j2d-cli:distZip to create a zip file that contains everything necessary to run.
SE makes use of a rotational electric powered area to disperse hugely electromobile molecules (like antibodies or surfactant micelles) in the course of a porous sample with out harming electrically billed structures in the tissue. This enables two-four day clearing of intact organs,
Our preformulated EasyIndex Alternative raises and homogenize the refractive index of delipidated tissue samples, rendering them fully transparent. This permits light-weight penetration in to the sample and assures the acquisition of significant-resolution, in-concentrate picture facts.
Megatome is often a novel microtome which allows for top-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with minimal tissue harm and information loss.
eFLASH is actually a quick tissue labeling strategy that enables for uniform full-organ staining in twenty rounds of labeling.
The SmartSPIM light-weight sheet megatomi.com microscope delivers unparalleled resolution and acquisition velocity all over intact tissue volumes, though its modular style and design helps you to enhance and customise particular person parts.
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This tends to crank out a feed directory within the javadoc2dash.outputLocation Listing. This directory will contain an XML file describing the feed
Possibly down load a launch or create a distribution zip as outlined earlier mentioned. Unzip the archive to a wanted locale.
Leverage the Apparent+ tissue clearing technique, as well as eFLASH and patented stochastic electrotransport systems, to fast distinct and label complete organs. Critical highlights and options consist of:
Our novel Defend tissue preservation strategy varieties intramolecular bonds employing polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.